Elevate your product line with
the unique Oil Marbles™ technology

Unmatched technology, unique performance

Our expertise is in creating solid lipid formulations for pharmaceuticals, food supplements, and cosmetics. These formulations are easier to handle, offer flexible dosing, and maintain a high oil content.

Our technology uses oil marbles — liquid droplets encapsulateed in a stable layer of fine solid particles. This prevents leaking and allows the oil marbles to stay separate and uniform in size, typically between 1 and 3 mm. We focus on oil-based marbles, ideal for poorly water soluble compounds. Innovation solution was proved by obtaining patents.

We’ve developed a special device to precisely manufacture these marbles, ensuring they meet specific requirements.

Our benefits

Enhanced bioavailability. Oil Marbles ensure efficient absorption of active ingredients. Already proved in vivo study. Clinical data are coming soon.

Elimination of the “food effect”. Oil Marbles allow for consistent efficiency regardless of food intake.

Personalization options. Tailor-made formulations to meet specific market needs.

Taste masking & Shelf-life Extension. Improves user experience and product longevity.

Eco-friendly. Our technology utilizes 100% biodegradable ingredients and operates without harmful solvents.

Low Temperature Process. With a maximum temperature of 60°C applied for a limited time, our process is designed to protect the integrity of heat-sensitive components.

Precise Mixtures. Our technology allows for the combination of individual particles, enabling the creation of highly accurate mixtures with multiple active ingredients.

Science behind MarbleMat

The technology of Oil Marbles was developed at the University of chemistry and technology, Prague at the Chobotix Lab. During recent years, the team constructed the pilot device Spheromat for manufacturing of precise Oil Marbles (between 1 to 3 mm in diameter). Huge technological progress was made through the TAČR Zeta grant, during which a semi-industrial scale Spheromat device was developed. In addition, several research papers have been published in prestigious international scientific journals. Thanks to the wide range of external and internal experts in our team we are able to deliver the expertise of pharmaceutical development. Marblemat is still in a close connection with university that give us the innovation spirit.

Learn more about our scientific background by clicking the buttons below.

SOLID ENCAPSULATION OF OIL MARBLES

Bioavailability Enhancement and Food Effect Elimination

Operating Limits and Parametric Sensitivity

Manufacturability of Surfactant-Enriched Oil Marbles

Use of the Oil Marbles™

Pharma

Our goal is to use Oil Marbles technology to create solid lipid formulations that combine the benefits of lipid-based products with the ease of handling solid particles. This allows for rapid development of multiple dosage strengths, making it ideal for personalized medicine. Additional benefits include the ability to mask taste and adjust the dissolution rate by simply changing the size of the marbles.

Pharma

Our aim is to prepare solid lipid formulation with the Oil Marbles technology, combining all the advantages of lipid-based products with increased processability of solid particles while providing the opportunity of fast development of multiple dosage strengths with possible application in personalized medicine. Additional advantages include possibility of taste masking and modification of dissolution rate by a simple change of geometry.

Nutrition

With our technology, we can create solid formulations of food supplements and additives that are typically difficult to handle. This enables the precise inclusion of valuable nutrients into diets, with the added benefit of potential taste enhancement.

Food

With our technology, we are capable of creating solid formulations of food supplements and additives which are otherwise hard to handle. We see the potential for precise addition of valuable nutrition components into customers‘ diets, potentially enhanced by taste modification.

Contract Development Service

Custom formulation development: Tailored products to meet specific market needs.
Prototype creation & testing: Ensuring the highest quality and effectiveness.
Complete support: We offer full assistance, covering both technical and regulatory issues.

Investing in our contract development services means gaining access to cutting-edge technology and expert support, enabling you to bring innovative products to the market faster and more efficiently.