THE NEXT GENERATION OF ENCAPSULATION TECHNOLOGY
MARBLEMAT • PHARMA TECH STARTUP
SOLID ENCAPSULATION OF OIL MARBLES.
Our strengths lie in the development of lipid formulations (of pharmaceutics, food supplements or cosmetics) in solid state, which inherently exhibit improved handling properties and offer dosing flexibility while maintaining a high oil content.
Our technology is based on oil marbles – round liquid droplets, covered by a highly stable layer of fine solid particles. The powder particles prevent wetting, leakage or coalescence, causing the marbles to behave as individual objects. Their size is uniform and can be varied from 1 to 3 mm, depending on their composition and manufacturing parameters. While a variety of liquids can be encapsulated in this manner, we are mostly focusing on oil-based (lipidic) marbles as an ideal vehicle for poorly water-soluble molecules. In case of formulations containing solid-state lipids, melted liquid marbles are produced in liquid state and subsequently cooled down to solidify.
Due to the technique’s uniqueness, we have developed our own device to produce melt liquid marbles. This device enables us to manufacture precise marbles of desired sizes and compositions, which affects their physical properties. It is currently in the process of being implemented into the GMP regime, which will give us the potential to meet all requirements presented by regulatory authorities.
We’re excited to announce that we’ll be exhibiting this year at CPHI Frankfurt 2022 in Frankfurt, Germany on 1-3 November 2022. Start your CPHI Journey online from 28 September during Connect to Frankfurt!
Come see us in person in Booth #91B70
LIPID BASED FORMULATION.
MARBLEMAT BENEFITS
SPHEROMAT WITH PERSONALIZED DOSAGE.
Individual particles with high oil content are perfect to optimize the dosage. Due to the highly customizable thin layer of various solid particles, the release kinetics of encapsulated molecules can be modified. And more?
SCIENCE BEHIND MARBLEMAT
The technology of oil marbles was developed at the University of chemistry and technology, Prague at the Chobotix Lab. During recent years, the team constructed the pilot device Spheromat for manufacturing of precise oil marbles (between 1 to 3 mm in diameter). Huge technological progress was made through the TAČR Zeta grant, during which a semi-industrial scale Spheromat device was developed. In addition, several research papers have been published in prestigious international scientific journals. Thanks to the wide range of external and internal experts in our team we are able to deliver the expertise of pharmaceutical development. Marblemat is still in a close connection with university that give us the innovation spirit.
MARBLEMAT COOPERATES
MARBLEMAT is supported by several partners, both from academia and government organizations. Our partners are:
MARBLEMAT TEAM
EXPERTS OF THE FIELD.
Our team involves internal and external experts to deliver advanced solid lipid products.
INTERNAL COLLABORATORS:
INTERNAL COLLABORATORS:
Ondřej Rychecký
Founder of Marblemat technology
Adéla Brejchová
Application development
Maximillián Prachár
Device improvement
Eva Králová
Application development
Martin Krov
GMP implementation
Matěj Novák
Pharmaceutical formulation
Marek Sejval
Marketing specialist
Tomáš Hortlík
Business development
EXTERNAL COLLABORATORS:
František Štěpánek
Scientific advisor, professor at UCT Prague
Jiří Moninec
GMP implementation
Zdeňěk Hušek
Mentor
MARBLEMAT CONTACT
MARBLEMAT CONTACT
LET’S TALK.
MARBLEMAT S.R.O.
IČO: 09089772
EMAIL: info@marblemat.eu
TEL: +420 608 115 098
Are you interested in our project? Would you like more information? Don’t hesitate to ask.